Thank-you for your enquiry. You are at an age where, typically, the skin starts to lose volume and begins to sag. We use dermal fillers to replace the volume that has been lost in the skin. Dermal fillers are made up of Hyaluronic acid, which is an ingredient that naturally occurs in your skin, so it is not in any way foreign to the skin at all. A good filler will enhance your skin by putting back "shape" where you have lost it. Because we are not injecting anything foreign to the skin, you are very unlikely to have any "reactions" to the filler. Some fillers (not all) contain a numbing agent to make the injection process more comfortable for patients, and if there is anything you may react to it would be the numbing agent (should you choose to have this type of filler). The worst that could happen is that you have some bruising from the injecting, which will resolve quite quickly, and you may have a bit of swelling for a day or two. Botox on the other hand does not give you volume at all. Many people think that Botox does the same thing as a filler, but the two could not be more different. Botox simply treats lines and dynamic wrinkles in the skin, by stopping the skin’s ability to "frown". So if it is volume you are needing, Botox would definitely not be an option for you. If youd like some info on the different types of fillers to consider, have a look at www.skinrenewal.co.za