This is a great question. You can exfoliate one to two times per week, and apply your hydration mask directly after exfoliating. So, exfoliate well, rinse your skin, and then apply your mask. Once you’ve exfoliated and all the dead, built up skin cells are removed, your skin will better absorb the active ingredients in the mask. It’s a great treatment to give yourself at home. If you have a sensitive skin, I would stick to once per week.