Hi and thank you for an interesting question. The products and ingredients that are applied in cosmeceuticals to the skin are often digested and broken down when ingested unfortunately. Even oral collagen products have not scientifically proven any statistical absorption at low molecular weights. Hyaluronic acid is really a very fragile molecule and has a large molecular size, which means that the body will not easily absorb it through the intestinal lining either. If one makes the molecule smaller, it won’t work as well. In my experience it is best used as an injection or a topical application. I hope that this helps.